Best’s disease, also known as Best’s vitelliform macular dystrophy, is a hereditary eye condition that primarily affects the macula, the central part of the retina responsible for sharp, detailed vision. Often first identified in childhood or adolescence, Best’s disease progresses through various stages, gradually impacting central vision as the macula deteriorates. Although the condition is rare, it can lead to significant visual impairment, especially if not monitored and managed carefully.